A 72 year-old woman with hypertension, diabetes, and an impaired memory, abruptly developed left sided weakness.
MRI axial Flair images - Note the numerous infarcts in the deep white matter bilaterally. This multi-lacunar state (a.k.a., Binswanger's disease) results in a subcortical dementia. Patients develop loss of memory and cognition, often along with focal sensory and motor changes. Patients are usually hypertensive and/or have diabetes. Other prominent features of the disease include urinary incontinence, difficulty walking, clumsiness, slowness of conduct, lack of facial expression, and speech difficulty.
05/20/06Revised
10/28/05.
The Electronic Curriculum is copyrighted 1998, Case Western
Reserve University
School of Medicine.