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A 72 year-old woman presented with an episode of transient slurred speech. There was a history in her mother and two aunts of progressive "small strokes" leading to dementia.
Flair MRI axial scans. Note the prominent white matter changes, both centrally and peripherally in the white matter. A similar MRI picture could be seen in advanced multiple sclerosis or an inherited disorder of white matter (i.e., leukodystrophy).
The Electronic Curriculum is copyrighted 1998, Case Western Reserve University School of Medicine.