% strPathPics = Session("strPathPicsL") imgBg = strPathPics + Session("strMedia") %>
A 34 year woman old presented with slowly progressive ataxia since childhood.
(Left) T2 Axial MRI; (Middle) T1 Axial MRI; (Right) T1 Sagittal MRI. In all the scans, note the severe atrophy of the cerebellum. Marked atrophy of the cerebellum is most often associated with genetic abnormalities, although severe cases of alcohol intake as well as paraneoplastic conditions can also result in cerebellar atrophy. In this case, the patient was demonstrated to have adult onset hexosaminidase A deficiency (Late Onset Tay Sachs disease).
The Electronic Curriculum is copyrighted 1998, Case Western Reserve University School of Medicine.