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A 24 year-old man developed focal seizures affecting the left side of his body.
MRI T1 weighted (MP-RAGE) with Gadolinium. Note the large low density mass in the right hemisphere. There is no contrast enhancement (note the contrast in the arteries and sinuses). Also, note that there is very little mass effect. This is a low grade glioma. Low-grade astrocytomas make up 15% of all primary intracranial brain tumors, and usually occur in young adults. Although biopsy is required to make a definitive diagnosis, the lack of contrast enhancement favors the diagnosis of a low grade glioma rather than a glioblastoma.
The Electronic Curriculum is copyrighted 1998, Case Western Reserve University School of Medicine.