A 33 year-old man had a twenty year history of MS presenting first with optic neuritis. Over the last ten years, he had progressive weakness, numbness and ataxia in the lower extremities.
Axial MRI Flair images: note the numerous areas of demyelination in multiple areas of the white matter. Most of the lesions are near the ventricles. Several are aligned perpendicular to the ventricles, a pattern which is highly characteristic of multiple sclerosis.
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