Neuroscience Clerkship

 

 

 

 

COMMON CAUSES OF ATAXIA IN CHILDREN

Ataxia in children is an uncommon but important sign as it is associated with only certain disorders. Like many conditions in pediatric neurology, most are rare. Below is a list of some of the more common pediatric disorders associated with ataxia.
 

Acute Ataxia

Drug Ingestion

Acute cerebellar ataxia (post-infectious cerebellitis; may follow chicken-pox, other infections or vaccinations)

• Miller-Fisher Variant of GBS

Acute/Subacute ataxia with prolonged or intermittent course
 

Myoclonic Encephalopathy (Dancing eye syndrome, often associated with Neuroblastoma)

Brain Tumors (hemorrhage)

Multiple sclerosis

Metabolic disorders

 

Chronic ataxia

Brain Tumors (usually infratentorial)

Cerebellar astrocytoma

Ependymoma of 4th ventricle

Medulloblastoma

Cerebellar Hemangioblastoma

 Head Trauma

 Cerebral Palsy

 Genetic

Friedrich's ataxia

Ataxia telangiectasia

Spinocerebellar ataxias (SCA)

Abetalipoproteinemia

Refsum’s disease

Hartnup’s disease

• Chronic drug ingestion (e.g., anti-epileptics)

• Vitamin E Deficiency

Congenital malformations (usually associated w/ mental retardation)


COMMON CAUSES OF ATAXIA IN DIFFERENT AGE GROUPS

 

Ataxia in children before 1 year of age

Congenital malformations

Mild arrested hydrocephalus

Cerebral Palsy

 

Ataxia in children between 1-5 years of age

Drug Ingestion

Post-infectious cerebellar ataxia

Myoclonic Encephalopathy and Neuroblastoma

Inborn Errors of Metabolism

Brain tumors

Ataxia Telangiectasia

Refsum’s disease

 

Ataxia in Children between 5-10 years

Drug Ingestion

Post-infectious cerebellar ataxia

Brain tumors

Genetic [e.g., Friedreich’s Ataxia; other spinocerebellar ataxias (SCAs)]

 

Ataxia in children above 10 years of age

Genetic [e.g., Friedreich’s Ataxia; other spinocerebellar ataxias (SCAs)]

Multiple Sclerosis