Neuroscience Clerkship

 

 

VISUAL FIELD DEFECTS

 
 

The neuroanatomy of the visual system allows for precise localization for many visual field defects. In order to understand how a given lesion results in a visual field defect, it is imperative to have a firm grasp of the neuroanatomy of vision.

An important rule to remember when assessing visual field defects is that a visual field defect involving only one eye, is from a lesion anterior to the optic chiasm. This is due to the fact that none of the fibers of the visual pathways originating from the ipsilateral eye cross until they reach the optic chiasm. On the other hand, if both visual fields are affected, then the lesion is either at or beyond the optic chiasm.

The diagram below shows the visual field defect resulting from a given lesion. Note, that the visual field defects are seen from the patient’s perspective. Thus, when viewing them, imagine that you are looking from behind the patient’s eyes. Try to figure out what visual field defect will result from each lesion.  Place the cursor over the lesion, the location of the lesion will appear. Then click the lesion, and the visual field deficit will appear with an explanation.

 

Retrobulbar Optic Nerve Optic Nerve Optic Chiasm Optic Tract Lateral Geniculate Nucleus Inferior Optic Radiations (Meyer's Loop through the Temporal Lobe) Superior Optic Radiations (Parietal Lobe) Optic Radiations Occipital Cortex


Differential diagnosis for given lesion of the visual pathways:

Optic nerve

Demyelinating (2nd to multiple sclerosis), inflammatory (sarcoidosis, lupus), tumor (menigioma, glioma), vascular (temporal arteritis, anterior ischemic optic neuropathy), toxic

Optic chiasm

Tumor (pituitary adenoma, craniopharygioma, menigioma), aneurysm (ICA), infectious (cystercercosis cyst)

Optic tracts

Stroke, tumor, aneurysm

Lateral geniculate body

Stroke (anterior choroidal artery), demyelination

Optic radiations

Stroke, tumor, s/p temporal lobe epilepsy surgery, infectious (abscess)

Occipital cortex

Vascular (stroke, AVM), tumor, trauma, infectious (abscess)

 

 

The device above performs Humphrey visual field testing, which is an automated visual field test. The disadvantage to this type of testing is that it requires significant patient cooperation. The patient sits in front of the concave dome seen on the left and stares at a central target. The computer program flashes small lights at different locations. The patient presses a button each time a flash of light is detected. The responses are compared to age-matched controls and a print-out is made showing the visual field as seen by the patient.