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A 33 year old man presented with slowly progressive ataxia, slurred speech and nystagmus since childhood.
Axial MRI scan shows severe atrophy of the cerebellum and pons. This genetic condition, once termed olivopontocerebellar atrophy (OPCA) is now included under the spinocerebellar ataxias (SCA), a large group of inherited disorders characterized by progressive ataxia and brainstem signs.
Revised
04/19/06.
The Electronic Curriculum is copyrighted 1998, Case Western Reserve University
School of Medicine.