A four-year old girl presented with a delay in motor milestones and seizures.

Axial MRI T1-weighted scan with Gadolinium. Note the large subependymal nodule on the right. This is a giant tuber in a patient with tuberous sclerosis (TS). In TS, several abnormalities may be present on brain imaging including, cortical tubers (hamartomas) subependymal nodules that usually calcify and are multiple and bilateral; and subependymal giant cell astrocytomas that are most frequently found at the foramen of Monro.

Revised 04/23/06.
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