Neuroscience Clerkship

 

 

ANTERIOR SPINAL ARTERY OCCLUSION

 

 

Occlusion of the anterior spinal artery produces a distinctive syndrome: loss of spinothalamic and corticospinal tract function with preservation of the dorsal column functions (as the latter is supplied by the two posterior spinal arteries).

Anterior cord ischemia typically presents the abrupt onset of radicular or diffuse back pain, flaccid weakness, sphincter dysfunction, and a sensory level for pain and temperature with preservation of the posterior column sensations of touch and position sense. The limbs involved and the sensory level depends on the level at which the ischemia occurs. While the region of the cord most at risk because of poor collateral circulation is T5-T7, any region of the cord can become ischemic.

Aortic disease is the most likely etiology for cord ischemia but cardiac emboli, coagulopathies, and vasculitides, are also potential causes.

Thus, the patient is paralyzed to a varying degree below the level of the stroke with complete loss of pain and temperature sensation, but with preservation of vibration and joint position sense.

Above: Vascular supply of the spinal cord. The anterior 2/3 of the spinal cord is supplied by the anterior spinal artery. This artery arises from contributions of both vertebral arteries in the lower brainstem. In addition, frequent anatomoses occur with branches of intercostal / radicular arteries down the spine (adapted from Netter, 1983).